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An illustration of the controlled direct effect of olanzapine relative to perphenazine on quality-of-life score, fixing Positive and Negative Syndrome Scale total score and extrapyramidal symptoms score at zero, while fixing percent weight gain from −7% to 11%, using data from the Clinical Antipsychotic Trials of Intervention Effectiveness, United States, 2000–2004. Dashed lines represent 95% confidence intervals.
