TABLE 1.
Intakes of dietary fatty acids and plasma fatty acid proportions among NHS and HPFS participants, according to CAD status1
| NHS (n = 1142) | HPFS (n = 1146) | |||
|---|---|---|---|---|
| CAD cases (n = 340) | Controls (n = 802) | CAD cases (n = 380) | Controls (n = 766) | |
| Dietary fatty acids intake, mg/d | ||||
| LA | 10,812.4 ± 4247.4 | 10,772.1 ± 3912.5 | 11,302.2 ± 4451.2 | 11,029.8 ± 4175.8 |
| ALA | 987.1 ± 402.6 | 966.2 ± 384.0 | 1084.3 ± 424.6 | 1062.9 ± 397.7 |
| DHA | 152.5 ± 109.6 | 154.5 ± 115.3 | 166.1 ± 136.9 | 168.1 ± 145.3 |
| EPA | 76.0 ± 63.3 | 79.8 ± 102.8 | 99.0 ± 140.7 | 101.6 ± 138.5 |
| AA | 74.1 ± 29.3 | 74.9 ± 29.5 | 81.4 ± 33.0 | 79.5 ± 33.8 |
| Total fat | 65,695.3 ± 21,810.8 | 64,502.2 ± 20,300.3 | 71,567.3 ± 25,406.4 | 69,568.5 ± 25,282.6 |
| Plasma fatty acid proportions, % of total fatty acids | ||||
| LA | 29.93 ± 4.79 | 30.28 ± 4.64 | 30.18 ± 4.59 | 30.58 ± 4.46 |
| ALA | 0.50 ± 0.17 | 0.47 ± 0.15 | 0.64 ± 0.25** | 0.60 ± 0.24 |
| AA | 6.95 ± 1.60*** | 7.53 ± 1.72 | 7.05 ± 1.73* | 7.27 ± 1.71 |
| EPA | 0.46 ± 0.28 | 0.47 ± 0.22 | 0.60 ± 0.37 | 0.64 ± 0.46 |
| DHA | 1.35 ± 0.57** | 1.49 ± 0.62 | 1.67 ± 0.76 | 1.75 ± 0.74 |
1Values are means ± SDs. Differences between cases and controls were compared by using t tests or Wilcoxon's Signed Rank tests. *P < 0.05; **P < 0.01; ***P < 0.0001. AA, arachidonic acid; ALA, α-linolenic acid; CAD, coronary artery disease; HPFS, Health Professionals Follow-Up Study; LA, linoleic acid; NHS, Nurses’ Health Study.