Figure 2. Kaplan-Meier Curves for Time to Dementia Onset for Standard Hypertension Definition Blood Pressure Groups.

Kaplan-Meier curves for time to dementia onset in the full analytic sample (N = 4738), and among younger (n = 2053) and older (n = 2685) subgroups based on 24-year midlife to late-life blood pressure patterns. Younger and older groups were defined based on median split (<74 vs ≥74 years of age). The median interquartile range (IQR) follow-up times for the midlife and late-life group were 5.0 (4.4-5.3) for normotension and normotension, 4.9 (4.4-5.3) for normotension and hypertension, 4.9 (4.3-5.3) for hypertension and hypertension, 4.9 (4.3-5.2) for hypertension and normotension, and 4.9 (4.2-5.2) years for the hypertension and hypotension group. The median (IQR) follow-up time for the groups with participants younger than 74 years of age were 5.0 (4.5-5.3) for normotension and normotension, 5.0 (4.4-5.3) for normotension and hypertension, 4.9 (4.4-5.3) for hypertension and hypertension, 5.0 (4.5-5.4) for hypertension and normotension, and 4.9 (4.3-5.3) years for the hypertension and hypotension group. The median (IQR) follow-up times for the groups with participants aged 74 years or older were 4.9 (4.3-5.2) for normotension and normotension, 4.9 (4.3-5.2) for normotension and hypertension, 4.8 (4.2-5.2) for hypertension and hypertension, 4.9 (4.2-5.2) for hypertension and normotension, and 4.9 (4.2-5.2) years for the hypertension and hypotension group. Participants with midlife hypertension and late-life normotension were not included in the standard hypertension definition analyses because of small sample size (n = 23).