Table 1. Baseline Characteristics of Clusters (Hospitals) and Patients.
| Characteristic | Study Groupa | |
|---|---|---|
| Intervention | Control | |
| Patients | ||
| Men | 441/817 (54.0) | 472/807 (58.5) |
| Age, mean (SD), y | 70.3 (13.6) | 68.4 (13.4) |
| Diabetes | 252/817 (30.8) | 232/806 (28.8) |
| Hypertension | 627/817 (76.7) | 592/807 (73.4) |
| Dyslipidemia | 224/817 (27.4) | 150/807 (18.6) |
| Current smoking | 129/817 (15.8) | 169/807 (20.9) |
| Family history of stroke | 62/817 (7.6) | 116/807 (14.4) |
| Family history of CAD | 53/817 (6.5) | 121/807 (15.0) |
| Prior stroke | 243/817 (29.7) | 213/807 (26.4) |
| CAD | 113/817 (13.8) | 156/807 (19.3) |
| Atrial fibrillation | 120/817 (14.7) | 74/807 (9.2) |
| Renal failure | 25/817 (3.1) | 32/807 (4.0) |
| Use of aspirin in the past month | 211/817 (25.8) | 201/807 (24.9) |
| Use of anticoagulants in the past month | 77/817 (9.4) | 68/807 (8.4) |
| Use of statins in the past month | 207/817 (25.3) | 190/807 (23.5) |
| Final diagnosis | ||
| AIS | 711/817 (87.0) | 723/807 (89.6) |
| TIA | 106/817 (13.0) | 84/807 (10.4) |
| Clusters | ||
| Neurologist available at ED | 13/19 (68.4) | 9/17 (52.9) |
| Mechanical thrombectomy capabilities | 17/19 (89.5) | 15/17 (88.2) |
| Stroke unit | 10/19 (52.6) | 7/17 (41.2) |
| Stroke protocol available at ED | 17/19 (89.5) | 17/17 (100) |
| Stroke protocol available at the hospital | 19/19 (100) | 17/17 (100) |
| JCI accreditation | 1/19 (5.3) | 3/17 (17.6) |
| Teaching hospital | 13/19 (68.4) | 15/17 (88.2) |
| Prior participation in multicenter clinical trial | 17/19 (89.5) | 15/17 (88.2) |
| Patients seen in ED per mo, median (IQR), No. | 1600 (425-3000) | 1400 (800-4000) |
| Baseline rate of composite adherence score, median (IQR)b | 77.1 (67.7-82.5) | 75.3 (66.2-79.8) |
Abbreviations: AIS, acute ischemic stroke; CAD, coronary artery disease; ED, emergency department; IQR, interquartile range, JCI, Joint Commission International; TIA, transient ischemic attack.
a
Unless otherwise indicated, data are expressed as number/total number (percentage) of patients or clusters.
b
Indicates primary outcome.