Table 3. Results of Quality Improvement Intervention for Clinical Cardiovascular Events, in Hospital and at 90 Days.
| Event | No./Total No. (%) | OR (95% CI) | P Value | |
|---|---|---|---|---|
| Intervention | Control | |||
| Prespecified clinical events (within 90 d) | ||||
| Stroke recurrence | 11/817 (1.3) | 5/807 (0.6) | 2.26 (0.78-6.49)a | .13 |
| Total mortality | 103/817 (12.6) | 95/807 (11.8) | 1.16 (0.68-2.01)a | .58 |
| Cardiovascular mortality | 17/817 (2.1) | 14/807 (1.7) | 1.53 (0.54-4.27)a | .42 |
| Disability (modified Rankin score <2)b | 274/662 (41.4) | 255/670 (38.1) | 1.11 (0.74-1.68) | .61 |
| Additional clinical events (in hospital) | ||||
| Hemorrhagic transformation | 42/817 (5.1) | 20/804 (2.5) | 2.11 (1.13-3.94) | .02 |
| Nonfatal cardiac arrest | 4/817 (0.5) | 3/805 (0.4) | 1.24 (0.17-8.90) | .83 |
| Major bleedingc | 12/817 (1.5) | 3/805 (0.4) | 5.15 (0.81-32.55) | .08 |
| Acute coronary syndrome | 17/817 (2.1) | 11/805 (1.4) | 1.51 (0.43-5.35) | .52 |
| Stroke recurrence | 7/817 (0.9) | 0/807 | NA | .93 |
| Total mortality | 22/817 (2.7) | 17/807 (2.1) | 1.67 (0.66-4.22) | .28 |
| Cardiovascular mortality | 17/817 (2.1) | 14/807 (1.7) | 1.64 (0.55-4.94) | .38 |
Abbreviations: NA, not applicable; OR, odds ratio.
a
Data are shown as hazard ratios (95% CI).
b
A modified Rankin score <2 indicates that the patient is independent.
c
Excludes central nervous system bleeding.