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. 2019 Aug 7;10:1858. doi: 10.3389/fimmu.2019.01858

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Copyright © 2019 Riani, Muller, Bour, Bernard, Antonicelli and Le Jan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Detection of macrophage-associated cytokines in serum and blister fluid (BF) of BP patients. The concentrations of a panel of M1-type (A) and M2-type (B) macrophage markers were measured in serum from control subjects (Control sera, n = 8) and in serum (BP sera, n = 12) and BF (n = 40) from patients with BP at time of diagnosis using the bead-based immunoassays LEGENDplex Human Macrophage/Microglia Panel and Human Th Cytokines Panel. Non-parametric unpaired Mann–Whitney's test was used to compare populations (^*p < 0.05; ^**p < 0.01; ^***p < 0.001).