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. 2019 Apr 17;317(1):F43–F51. doi: 10.1152/ajprenal.00083.2019

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Fig. 3. — Bladder capacity was significantly increased in both male and female control rats (n = 8 female rats and n = 6 male rats), rats with acute (4 h) cyclophosphamide (CYP)-induced cystitis (n = 8 female rats and n = 6 male rats), and rats with chronic CYP-induced cystitis (n = 6 female rats and n = 6 male rats). After VEGF/VEGF receptor 2 (VEGFR2) signaling blockade with Ki-8751, bladder capacities significantly increased in female control rats (P ≤ 0.01) and female rats with acute (P ≤ 0.05) and chronic (P ≤ 0.05) CYP-induced cystitis (A) as well as in male control rats (P ≤ 0.01) and male rats with acute (P ≤ 0.05) and chronic (P ≤ 0.01) CYP-induced cystitis (B). Values are means ± SE. *P < 0.05; **P < 0.01.