Table 1.

Baseline characteristics of WKY and GK rats used in present study

	WKY	GK
Mass, g	405 ± 11	347 ± 9*
MAP, mmHg	103 ± 5	105 ± 6
Glucose, mg/dl	86 ± 5	166 ± 12*
Insulin, ng/ml	1.0 ± 0.3	6.6 ± 0.8*
Cholesterol, mg/dl	79 ± 14	98 ± 13
Triglycerides, mg/dl	118 ± 15	211 ± 16*
Nitrotyrosine, ng/ml	11 ± 3	34 ± 5*
TNF-α, pg/ml	1.3 ± 0.4	5.7 ± 0.7*
IL-1β, pg/ml	6.5 ± 0.6	10.9 ± 0.9*
MCP-1, pg/ml	35.6 ± 4.1	58.5 ± 5.9*
RANTES, pg/ml	29.4 ± 4.8	88.5 ± 11.4*

Values are means ± SE; n = 12 rats for both groups [Wistar Kyoto (WKY) and Goto-Kakizaki (GK)]. All animals were ~17 wk of age. MCP-1, monocyte chemotactic protein-1; MAP, mean arterial pressure; RANTES, regulated on activation normal T-expressed and presumably secreted.

^*P < 0.05 vs. WKY.