Table 1.
Baseline characteristics of WKY and GK rats used in present study
WKY | GK | |
---|---|---|
Mass, g | 405 ± 11 | 347 ± 9* |
MAP, mmHg | 103 ± 5 | 105 ± 6 |
Glucose, mg/dl | 86 ± 5 | 166 ± 12* |
Insulin, ng/ml | 1.0 ± 0.3 | 6.6 ± 0.8* |
Cholesterol, mg/dl | 79 ± 14 | 98 ± 13 |
Triglycerides, mg/dl | 118 ± 15 | 211 ± 16* |
Nitrotyrosine, ng/ml | 11 ± 3 | 34 ± 5* |
TNF-α, pg/ml | 1.3 ± 0.4 | 5.7 ± 0.7* |
IL-1β, pg/ml | 6.5 ± 0.6 | 10.9 ± 0.9* |
MCP-1, pg/ml | 35.6 ± 4.1 | 58.5 ± 5.9* |
RANTES, pg/ml | 29.4 ± 4.8 | 88.5 ± 11.4* |
Values are means ± SE; n = 12 rats for both groups [Wistar Kyoto (WKY) and Goto-Kakizaki (GK)]. All animals were ~17 wk of age. MCP-1, monocyte chemotactic protein-1; MAP, mean arterial pressure; RANTES, regulated on activation normal T-expressed and presumably secreted.
P < 0.05 vs. WKY.