Table 4.

Association between low-frequency variants at 2q24 and DPN

Low-frequency variant	Position	Alleles*	MAF	r2‡	Univariable				Multivariable†
					Low-frequency variant		rs13417783		Low-frequency variant		rs13417783
					OR	P	OR	P	OR	P	OR	P
rs16852465	2:167524744	G/A	0.036	0.009	1.94	3.8E–04	0.64	1.9E–09	1.80	1.7E–03	0.66	2.1E–08
rs1509652	2:167589745	C/T	0.038	0.01	1.76	1.1E–03	0.64	1.9E–09	1.63	5.3E–03	0.66	2.0E–08
rs11884905	2:167611786	C/T	0.037	0.009	1.84	6.7E–04	0.64	1.9E–09	1.70	3.1E–03	0.66	2.1E–08
rs6721669	2:167636784	T/C	0.035	0.009	1.98	2.9E–04	0.64	1.9E–09	1.84	1.3E–03	0.66	2.2E–08
rs6755015	2:167666021	T/C	0.040	0.008	1.68	2.5E–03	0.64	1.9E–09	1.56	1.0E–02	0.66	1.6E–08

*Minor allele/major allele. †Results of regression models including one of the low-frequency variants along with rs13417783 as DPN predictors.

‡r² with rs13417783.