Table 2.
24-h, nighttime, daytime, morning systolic and diastolic blood pressure, pulse pressure in resistant hypertension and well-controlled hypertension groups at baseline and after three and six months of the study
| Parameter (mmHg) | Time of measurement | Resistant | Hypertension | Well-controlled hypertension | P value |
|---|---|---|---|---|---|
| Office SBP | At baseline | 150±24 | 132±8.5 | <0.001 | |
| After 3 months | 137.5±17 | P=0.004* | 129.7±10 | 0.1 | |
| After 6 months | 140±24 | P=0.08 | 130.7±11 | 0.2 | |
| Office DBP | At baseline | 90±14 | 80.5±7.5 | <0.005 | |
| After 3 months | 83±11 | P=0.001* | 77.7±7 | 0.1 | |
| After 6 months | 84.4±13 | P=0.04** | 80.7±8 | 0.2 | |
| SBP ABPM | At baseline | 127±17 | 119±12 | <0.05 | |
| After 3 months | 126±15 | P=0.20 | 120±11 | 0.1 | |
| After 6 months | 127±18 | P=0.60 | 119±9 | 0.1 | |
| DBP ABPM | At baseline | 75.4±11 | 72.6±7.1 | 0.3 | |
| After 3 months | 73.8±11 | P=0.10 | 71.9±6.5 | 0.5 | |
| After 6 months | 74.6±12 | P=0.40 | 71.9±5.2 | 0.4 | |
| Daytime SBP ABPM | At baseline | 131.3±16 | 122.4±12 | <0.05 | |
| After 3 months | 131.4±14 | P=0.30 | 124±12 | 0.1 | |
| After 6 months | 130±16 | P=0.30 | 123±10 | 0.1 | |
| Daytime DBP ABPM | At baseline | 77.8±11 | 75±7 | 0.3 | |
| After 3 months | 77.5±10 | P=0.30 | 74.7±7 | 0.3 | |
| After 6 months | 76.2±11 | P=0.20 | 74±5 | 0.4 | |
| Nighttime SBP ABPM | At baseline | 116.7±20 | 109.5±15 | 0.2 | |
| After 3 months | 111.6±17 | P=0.07 | 107±12 | 0.3 | |
| After 6 months | 119±25 | P=0.70 | 107±9 | 0.05 | |
| Nighttime DBP ABPM | At baseline | 67.4±13 | 64.8±9 | 0.8 | |
| After 3 months | 65.7±12 | P=0.40 | 63±6 | 0.4 | |
| After 6 months | 69±15 | P=0.90 | 64±6 | 0.2 | |
| Pulse pressure ABPM | At baseline | 53.2±11 | 46.4±9 | <0.05 | |
| After 3 months | 52.3±8 | P=0.20 | 48±9 | 0.1 | |
| After 6 months | 52.5±10 | P=0.40 | 47±9 | 0.1 | |
| Nighttime pulse pressure ABPM | At baseline | 49±11 | 44.2±9 | 0.4 | |
| After 3 months | 46±9 | P=0.03** | 44±9 | 0.4 | |
| After 6 months | 50±14 | P=0.80 | 43.5±8 | 0.1 | |
| Daytime pulse pressure ABPM | At baseline | 53.5±10 | 47.6±10 | <0.05 | |
| After 3 months | 54.7±9 | P=0.98 | 49.5±10 | 0.06 | |
| After 6 months | 53±9 | P=0.50 | 49±9 | 0.1 | |
| Morning SBP ABPM | At baseline | 136.6±25 | 125±19 | 0.06 | |
| After 3 months | 136±16 | P=0.40 | 125±20 | 0.05 | |
| After 6 months | 116.6±37 | P=0.07 | 120±17 | 0.3 | |
| Morning DBP ABPM | At baseline | 80.5±15 | 73.2±10 | 0.05 | |
| After 3 months | 80.3±14 | P=0.50 | 74±12 | 0.1 | |
| After 6 months | 75.2±19 | P=0.15 | 74±12 | 0.3 |
ABPM=automatic blood pressure monitoring; BP=blood pressure; DBP=diastolic blood pressure; Morning SBP and DBP=blood pressure mean during 1st hour after waking up; SBP=systolic blood pressure.
Data are presented as mean±SD.
*P<0.005 for the difference in the group of resistant hypertension versus baseline value.
**P<0.05 for the difference in the group of resistant hypertension versus baseline value.