Table 1.

Description of Stressors Used in Chronic Variable Stress Model

Stressor	Description
Social stress	Subjects placed in an empty, previously occupied cage for 3 h
Restraint stress	Subjects placed in a closed, ventilated tube for 30 min
Novel object exposure	Novel objects (8 marbles) placed in each cage overnight
Damp sawdust	Subjects remained in cages with damp bedding (125 mL of water added) for 3 h
Empty cage	Subjects placed in a cage without sawdust for 3 h
Light cycle disturbance	Subjects exposed to continuous overhead light for 36 h
Noise exposure	Subjects exposed to a pink noise (80 dB) for 8 h
Cage tilt	Cages tilted backward (45°) for 3 h
Predator odor	Subjects exposed to cat odor for 60 min