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Increased UCP1 expression in visceral omental adipose tissue of patients with BMI higher than 50 kg/m2. UCP1 mRNA was quantified in VAT by qPCR, normalized for HMBS and compared in PWO with BMI lower than 50 (n = 43) and with BMI higher that 50 (n = 18). Data were reported as a box plot, with 25th, 75th percentile and median values. Statistical analysis was performed by the Mann-Whitney U-test (**p < 0.01).
