Table 1.

Overview of study outcomes

Study outcomes	Definition
pDDI	Two potentially interacting medications administered concomitantly which could result in an actual DDI.
Clinically relevant pDDI	A pDDI considered clinically relevant for the ICU setting, according to the results from our Delphi procedure.
ADE related to DDI	A DDI that resulted in patient harm.
Appropriately handled pDDI	Two potentially interacting medications were administered concomitantly (pDDI), but there is evidence that adequate measures were taken to prevent patient harm or diminish the risk of patient harm.