Table 3.

Syndromic approach to the clinical presentation of MGRS

Clinical syndrome/presentation	Associated MGRS entities
NS	Amyloidosis (glomerular), MIDD
Nephritic-nephrotic syndrome (proteinuria, hematuria, hypertension, low complement levels, and renal insufficiency)	PGNMID, ITG, FG, C3G with monoclonal immunoglobulin, cryoglobulinemic GN
Acute renal failure	TMA, MIDD, and crystalglobulinemia
Proteinuria/progressive renal insufficiency	LCPT (with/without FS), MIDD, amyloidosis (tubulointerstitial and vascular), CSH, TMA

Adapted from Sethi et al²⁹ with permission.