Table 3.
Distribution of PDCD6 rs3756712 genotypes among the 358 patients with lung cancer and the 716 matched controls
Genetic model | Genotype | Controls | Patients | OR (95% CI) | p-valuea | ||
---|---|---|---|---|---|---|---|
n | % | n | % | ||||
rs3756712 | |||||||
Codominant | TT | 398 | 55.6% | 210 | 58.7% | 1.00 (reference) | |
GT | 254 | 35.5% | 127 | 35.4% | 0.95 (0.72–1.24) | 0.6969 | |
GG | 64 | 8.9% | 21 | 5.9% | 0.62 (0.37–1.05) | 0.0716 | |
Ptrend | 0.1974 | ||||||
Recessive | TT+GT | 652 | 91.2% | 337 | 94.1% | 1.00 (reference) | |
GG | 64 | 8.9% | 21 | 5.9% | 0.63 (0.38–1.06) | 0.0544 | |
Dominant | TT | 398 | 55.6% | 210 | 58.7% | 1.00 (reference) | |
GT+GG | 318 | 44.4% | 148 | 41.3% | 0.88 (0.68–1.14) | 0.3382 |
Note: aBased on Chi-squared test without Yates’ correction .
Abbreviations: CI, confidence interval; OR, odds ratio; Ptrend, p for trend.