Fig. 2.

Chemotherapy-induced premature ovarian insufficiency (POI) mice model. A Vaginal exfoliative cell smear and ovary section of normal mice (a–d, × 100; i, × 40; j, × 200) and POI mice (e–h, × 100; k, × 40, l, × 200). B Comparison of the follicles and the proportion of atretic follicles between CTX/BUS+ group and CTX/BUS− groups (*P < 0.05). C E2 and FSH levels determined by ELISA 14 days after CTX/BUS administration (*P < 0.05). E2 oestradiol, FSH follicle-stimulating hormone, CTX/BUS+ CTX/BUS administration, CTX/BUS− CTX/BUS non-administration