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. 2019 Aug 14;10:250. doi: 10.1186/s13287-019-1327-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — HUCMSC-MVs activate the PI3K/AKT signaling pathway of the ovaries in POI mice. a The protein expressions of total-AKT, p-AKT, and VEGF in the ovaries of the three groups. b The protein expression of VEGF in the three groups. c The protein expression of total-AKT in the three groups. d The protein expression of p-AKT in the three groups (*P < 0.05 vs the control group, ^#P < 0.05 vs the POI-MVs group)