Table 3.

Multivariable adjusted^a HR and 95% CI for mortality risk associated with wine, beer, or liquor consumption from age 15 years until breast cancer diagnosis

	Person-years	Breast cancer-specific mortality		Mortality due to causes other than breast cancer		All-cause mortality
		No. Death	HR (95% CI)	No. Death	HR (95% CI)	No. Death	HR (95% CI)
Non-drinkers	14,468	382	Referent	87	Referent	469	Referent
Wine, average drinks/week
< 1	9353	191	0.97 (0.78–1.19)	43	0.83 (0.56–1.23)	234	0.92 (0.77–1.11)
1–< 3	5106	80	0.78 (0.60–1.03)	30	1.04 (0.67–1.61)	110	0.83 (0.66–1.04)
≥ 3	2560	35	0.76 (0.53–1.11)	9	0.58 (0.29–1.20)	44	0.73 (0.53–1.01)
Ptrend			0.06		0.27		0.04
Beer, average drinks/week
< 1	7652	143	0.82 (0.66–1.02)	47	1.37 (0.93–2.02)	190	0.91 (0.75–1.10)
1–< 3	3706	71	0.94 (0.72–1.23)	29	1.24 (0.79–1.95)	100	0.99 (0.79–1.25)
≥ 3	2471	57	0.79 (0.59–1.07)	17	0.73 (0.42–1.27)	74	0.77 (0.59–1.00)
Ptrend			0.24		0.19		0.08
Liquor, average drinks/week
< 1	10,978	218	1.09 (0.88–1.34)	54	0.99 (0.67–1.46)	272	1.08 (0.90–1.30)
1–< 3	4330	84	0.97 (0.74–1.27)	35	1.17 (0.75–1.82)	119	1.03 (0.82–1.30)
≥ 3	2572	54	0.99 (0.72–1.37)	25	1.07 (0.65–1.74)	79	1.04 (0.80–1.35)
Ptrend			0.74		0.14		0.98

Abbreviations: HR hazard ratio, CI confidence interval

^aAll models are stratified by age at diagnosis, and include study site, race, education, household income, number of mammograms within the 5 years before breast cancer diagnosis, body mass index 5-years before diagnosis, number of comorbidities before breast cancer diagnosis, smoking history, stage, estrogen receptor status, histologic type of breast cancer tumor, and consumption of other types of alcohol using categories of drinks/week (wine adjusted for beer and liquor, beer adjusted for wine and liquor, liquor adjusted for beer and wine)