Fig. 8.

Fibrosis in WT, miR-146a^−/−, mdx, and miR-146a^−/−mdx hind limb muscles. a Tgfb1, b Mmp-9, and c Col1a1 level in GM; qRT-PCR. d Semi-quantitative analysis of collagen deposition in GM; trichome staining; representative photos. e Percentage of FAPs; (CD45⁻CD31⁻Sca1⁺α7integrin⁻CD34⁺); flow cytometry. Mean +/− SEM; n = 5–11; *− p ≤ 0.05; **− p ≤ 0.01; ***− p ≤ 0.001. Scale bars 100 μm