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Pathological alteration of ovaries and uterus of rats exposed to ZnO NPs.
|
| ||||||
| Tissue | Ovary | Uterus | ||||
| Groups | Hyperemia | Inflammatory cell infiltration | Increase corpus Luteum | Fibrosis | Epithelial destruction | Gland hyperplasia |
| Control | – | – | – | – | – | – |
| Sham | – | – | – | – | – | – |
| ZnO NPs dose | ||||||
| 4 mg/kg | – | – | – | – | – | – |
| 8 mg/kg | – | – | – | – | – | – |
| 25 mg/kg | + + | + + | – | – | ||
| 50 mg/kg | + + | + + | – | – | ||
| 100 mg/kg | ++ | ++ | + ++ | + + | ||
| 200 mg/kg | + ++ | – | ++ | + ++ | ||
