Table 3.

Biochemical assay of serum and MDA level in the ovary exposed to ZnO NPs.

Groups	Estrogen	Progesterone	MDA of Ovary nmol/mg
Control	22.66 $\pm$ 1.84${}^{b,c}$	5.916 $\pm$ 0.56${}^{a,b}$	0.67 $\pm$ 0.03${}^a$
Sham	24.3 $\pm$ 1.59${}^{c,d}$	6.08 $\pm$ 0.48${}^{a,b}$	0.68 $\pm$ 0.03${}^a$
ZnO NPs dose
4 mg/kg	28.46 $\pm$ 2.11${}^{d,e}$	8.44 $\pm$ 0.82${}^c$	0.678 $\pm$ 0.03${}^a$
8 mg/kg	33.86 $\pm$ 1.84${}^e$	8.19 $\pm$ 0.66${}^c$	0.68 $\pm$ 0.02${}^a$
25 mg/kg	31.99 $\pm$ 3.18${}^e$	7.44 $\pm$ 0.88${}^{b,c}$	1.06 $\pm$ 0.08${}^b$
50 mg/kg	31.19 $\pm$ 1.13${}^e$	6.02 $\pm$ 0.9${}^{a,b}$	1.6 $\pm$ 0.13${}^c$
100 mg/kg	18.42 $\pm$ 1.65${}^{a,b}$	5.68 $\pm$ 0.37${}^{a,b}$	2.73 $\pm$ 0.21${}^d$
200 mg/kg	16.42 $\pm$ 0.92${}^a$	5.23 $\pm$ 0.42${}^a$	3.59 $\pm$ 0.21${}^e$
Note: Data presented as mean $\pm$ SE; ${}^{a,b,c,d,e}$: Different letters a, b and c, etc., to show statistically significant differences between the groups.