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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Curr Environ Health Rep. 2019 Jun;6(2):53–61. doi: 10.1007/s40572-019-00229-5

Table 1.

The four main possible questions in mixtures analyses.

1. Are there specific patterns of exposure in the study population?
2. Which are the toxic agents in the mixture? Or, what are the independent effects of each mixture member on the health outcome of interest?
3. Are there synergistic effects or interactions among mixture members?
4. What is the overall effect of the mixture on the outcome of interest?