Table 3.

Cox proportional hazards model for CLAD by allograft injury, infection and colonization

	Univariable						Multivariable ^ƚ
	HR		95% CI			p-value	HR		95% CI			p-value
ALI	1.6	^**	1.1	-	2.3	0.0059	1.4		0.96	-	1.9	0.0804
OP	1.6	^**	1.1	-	2.1	0.0053	1.3		0.92	-	1.8	0.1471
LB	1.3		0.99	-	1.8	0.0605
AR	1.5	^**	1.2	-	2.0	0.0029	1.3		0.96	-	1.7	0.1011
Infection	2.1	^***	1.5	-	2.9	0.0001	1.8	^***	1.3	-	2.6	0.0008
Colonization	1.0		0.7	-	1.3	0.7717

Definition of abbreviations: CLAD = chronic lung allograft dysfunction, HR = hazards ratio, CI = confidience interval, ALI = acute lung injury, OP = organizing pneumonia, LB = lymphocytic bronchiolitis, AR = acute rejection, A1 = grade A1 acute rejection.

^ƚ

Multivariable model adjusted for variables listed.

P-values: < 0.05,

^**

< 0.01,

^***

< 0.001.