Increased activation of AKT, ERK1/2-MAPKs and HGF/c-Met signalling in BMP9-KO livers upon DDC treatment. A, Phosphorylated AKT (P-AKT) and ERK1/2-MAPKs (P-ERK1/2) levels in liver were analysed by western blot. One experiment of 3 is shown (left panel). Optical density values are mean ± SEM of 4–9 animals per group (right panel). B, Phosphorylated-MET (P-MET) levels in liver were analysed by western blot. One experiment of 3 is shown (left panel). Optical density values are mean ± SEM of 5–10 animals per group (right panel). Data were compared with the untreated group or as indicated, *P < .05, **P < .01, ***P < .001