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. Author manuscript; available in PMC: 2019 Aug 14.
Published in final edited form as: Liver Int. 2018 May 25;38(9):1664–1675. doi: 10.1111/liv.13879

FIGURE 5.

FIGURE 5

Decreased BMP9 expression and signalling in liver upon DDC treatment. A, Bmp9 mRNA levels in liver of WT animals after DDC treatment were determined by RT-qPCR. Data are mean ± SEM of 3–7 animals per group; (f.c.): fold change. B, Alk1, Alk2 and Bmpr2 mRNA levels in liver of WT animals were determined by RT-qPCR. Data are mean ± SEM of 3 animals per group; (f.c.): fold change. C, BMP9 and phosphorylated SMAD1,5,8 (P-SMAD1,5,8) levels in liver were analysed by western blot. One experiment of 2–3 is shown (left panel). Optical density values are mean ± SEM of 4–10 animals per group (right panel). Data were compared with the untreated group or as indicated, *P < .05 and ***P < .001