Table 2.
Demographic and clinical characteristics of human kidney transplant patients in study cohort.
| All biopsy (n = 56) | No rejection (n = 17) | Borderline (n = 22) | TCMR (n = 7) | AMR (n = 10) | ||
|---|---|---|---|---|---|---|
| Mean age (years) [SD] | 52.2 [14.5] | 53.0 [13.4] | 49.4 [14.4] | 45.1 [18.2] | 58.1 [7.4] | |
| Male : female (n) | 37:19 | 13:4 | 13:9 | 4:3 | 7:3 | |
| First transplant (n) | 48 | 13 | 20 | 7 | 8 | |
| Transplant type | DBD (n) | 34 | 10 | 12 | 5 | 7 |
| DCD (n) | 8 | 2 | 4 | 2 | 0 | |
| Cadaveric-NOS (n) | 10 | 4 | 4 | 0 | 2 | |
| Living donor (n) | 4 | 1 | 2 | 0 | 1 | |
| Median HLA match | 4 | 4 | 5 | 4 | 4 | |
| DSA present (n) | 5 | 2 | 0 | 0 | 3 | |
| cPRA | 0% (n) | 31 | 11 | 14 | 3 | 3 |
| >0–95% (n) | 4 | 1 | 2 | 0 | 1 | |
| >95% (n) | 2 | 2 | 0 | 0 | 0 | |
| Unavailable | 19 | 3 | 6 | 4 | 6 | |
| Biopsy within 3 m of transplantation (n) | 37 | 13 | 14 | 3 | 7 | |
| Mean creatinine prior to biopsy (μmol/L) [SD] | 219.1 [106.7] | 284.9 [288.7] | 222.0 [135.8] | 145.0 [54.4] | 267.1 [135.1] | |
| Patients receiving haemodialysis at biopsy (n) | 15 | 6 | 7 | 1 | 1 | |
DBD, donor after brain death; DCD, donor after circulatory death; Cadaveric-NOS, Cadaveric-Not otherwise specified; HLA, human leukocyte antigens; DSA, Donor-specific antibodies (pre-existing); cPRA, calculated Panel Reactive Antibodies (at transplantation).