Scheme 3.
Synthesis of the mannose precursor. Reagents and conditions: a) Zn(OAc)2·H2O, abs. MeOH, rt, 20 h, 60%; b) BrCH2COOC(CH3)3, K2CO3, dry DMF, rt, 2 h, 81%; c) TFA, dry DCM, rt, 1,5 h, 72%.
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