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. 2019 Aug 7;6:65. doi: 10.3389/fmolb.2019.00065

Figure 2.

Figure 2

Common features of colorectal cancer (CRC)-related RNA-Binding Proteins (RBPs). (A) CRC RBPs RNA targets according to POSTAR2 database. Circle sizes are correlated with the number of targets of each protein; shared RNA targets are shown in the middle. (B) A network showing CRC RBPs protein-protein interactions from experimental data and databases (interaction score: > 0.9). (C) Gene set enrichment analysis showing all significantly enriched terms concerning Gene Ontology (Molecular Function, Biological Process, and Cellular Component), Reactome, Transfac, miRTasBase, and Human Protein Atlas through g:Profiler (https://biit.cs.ut.ee/gprofiler/gost). The size of the circle is correlated with the number of genes overrepresented in association with certain type of molecular function or biological process. P-value adjusted (Padj) for multiple testing using Benjamini-Hochberg method.