Table 1.
Clinical characteristics of patients with sepsis and controls.
| Parameter | Patients with sepsis (n = 26) | Control subjects (n = 18) | P-value |
|---|---|---|---|
| Males, percentage (number) | 61.5 (16) | 61.1 (11) | 0.382 |
| Age, years (range) | 50 (32 to 78) | 53 (38 to 82) | 0.057 |
| SOFA score at admission, median (range) | 7.6 (3 to 16) | 5.9 (3 to 13) | 0.055 |
| APACHE II score at admission, median (range) | 16.5 (12 to 32) | 14.7 (8 to 24) | 0.062 |
| 28-day mortality, number (percentage) | 5 (19.23) | 4 (22.22) | 0.217 |
| Ventilation days, median days (range) | 5.5 (2 to 17) | 9.6 (2 to 26) | <0.001 |
| Length of ICU stay, median days (range) | 7.5 (3 to 22) | 9.2 (4 to 32) | 0.052 |
| Length of hospitalization, median days (range) | 16.4 (7 to 36) | 25.6 (6 to 89) | 0.008 |
| White blood cell at intake, mean (× 109/L) (range) | 13.66 (2.8 to 38.5) | 10.12 (5.8 to 14.5) | 0.032 |
| Absolute lymphocyte count, median (× 109/L) (range) | 0.71 (0.28 to 1.22) | 1.42 (0.98 to 2.31) | <0.001 |
| Procalcitonin, median (nanogram /L) (range) | 45.5 (10 to 286) | 0.32 (0.05 to 1.32) | <0.001 |
| C-reactive protein, median (milligram /L) (range) | 82.4 (42 to 142) | 47.5 (22 to 92) | <0.001 |
| Shock*, number (percentage) | 20 (76.9) | 1 (5.56) | <0.001 |
| Biliary tract infection, number (percentage) | 6 (23.1) | n/a | n/a |
| Urinary system infection, number (percentage) | 9 (34.6) | n/a | n/a |
| Pelvic and abdominal cavity infection, number (percentage) | 4 (15.4) | n/a | n/a |
| Other site infection, number (percentage) | 7 (26.9) | n/a | n/a |
APACHE II, Acute Physiology and Chronic Health Evaluation II; SOFA, Sequential [Sepsis-related] Organ Failure Assessment; n/a, Not Applicable; Shock*, the patients with septic shock can be clinically identified by a vasopressor requirement to maintain a mean arterial pressure of 65 mm Hg or greater and serum lactate level >2 mmol/L (> 18 mg/dL) in the absence of hypovolemia (24).