Figure 3. β-Amyloid as detected by [11C]PiB was positively correlated with both neurofibrillary tangles and Lewy bodies.

Partial correlations controlling for the interval between PET and autopsy: (A) neurofibrillary tangles (NFT) stage with [¹¹C]Pittsburgh compound B (PiB) (r = 0.73, p = 0.001), (B) Lewy body stage with PiB (r = 0.54, p = 0.025), and (C) Lewy body stage with [11C]Altropane (p = 0.21). Filled circles indicate dementia with Lewy bodies. Open diamonds, Parkinson disease with mild cognitive impairment and Parkinson disease with dementia. DAT = dopamine transporter; SUVR = standard uptake value ratio.