TABLE 2.
CT | HF | HF-B | |
Non-esterified fatty | 0.39 ± 0.03 | 0.36 ± 0.03 | 0.41 ± 0.05 |
acids (mM) | |||
Triglycerides (mM) | 0.48 ± 0.01 | 0.56 ± 0.04 | 0.46 ± 0.03 |
Glycemia (mg/dl) | 134.50 ± 5.21a | 176.90 ± 3.13b | 177.30 ± 5.54b |
Insulinemia (pM) | 35.02 ± 12.94a | 71.29 ± 11.83b | 36.98 ± 6.72a |
HOMA | 1.74 ± 0.67a | 4.52 ± 0.79b | 2.59 ± 0.43ab |
Cholesterol (mM) | 1.50 ± 0.05a | 1.98 ± 0.07b | 1.97 ± 0.06b |
HDL-CHO (mM) | 0.08 ± 0.00a | 0.12 ± 0.00b | 0.13 ± 0.01b |
Ghrelin (pg/ml) | 756.10 ± 165.00 | 426.80 ± 66.93 | 453.30 ± 69.65 |
PYY (pg/ml) | 39.23 ± 10.60 | 60.79 ± 2.50 | 54.85 ± 6.38 |
GIP (pg/ml) | 62.47 ± 8.79 | 76.18 ± 8.47 | 62.42 ± 7.84 |
GLP-1 (pg/ml) | 208.70 ± 40.42 | 273.40 ± 64.98 | 187.70 ± 67.83 |
Serum parameters after a short-term high fat diet (HFD). Mice fed a control diet and delivery vehicle-skimmed milk in drinking water (CT), mice fed a HFD and delivery vehicle-skimmed milk in drinking water (HF), and mice fed a HFD supplemented with a suspension of 5 × 108 cfu/mouse/day of B. animalis IPLA R1 strain in skimmed milk (HF-B) added to the drinking water. Data are expressed as the mean ± SEM. Data with different superscript letters are significantly different at p < 0.05 according to One-way analysis of variance statistical analysis followed by Tukey post hoc. GIP, glucose-dependent insulinotropic polypeptide; GLP-1 glucagon like peptide-1; HDL-CHO, high density lipoprotein cholesterol (HDL-Cholesterol). HOMA, homeostasis model assessment.