Table 1.
Summary statistics stratified by sex, condition and genotype for adult body weight, thymus, adrenal and spleen weight (expressed per 100 g body weight).
MALES | FEMALES | |||||||
---|---|---|---|---|---|---|---|---|
MRflox/wt | MRCamKCre/wt | MRflox/wt | MRCamKCre/wt | |||||
Control (11) | ELS (11) | Control (10) | ELS (11) | Control (11) | ELS (11) | Control (13) | ELS (11) | |
Body weight (g) | 29.5 ± 1.06 | 28.6 ± 2.79 | 27.7 ± 2.44 | 30.3 ± 2.17 | 27.0 ± 4.65 | 24.8 ± 4.39# | 25.2 ± 3.86 | 22.3 ± 1.96# |
Thymus (mg/100 g BW) | 0.139 ± 0.026 | 0.127 ± 0.023 | 0.135 ± 0.020 | 0.119 ± 0.015 | 0.185 ± 0.061 | 0.209 ± 0.07 | 0.229 ± 0.068 | 0.231 ± 0.035 |
Adrenals (mg/100 g BW) | 0.010 ± 0.003 | 0.011 ± 0.002 | 0.012 ± 0.002 | 0.011 ± 0.003 | 0.017 ± 0.004 | 0.02 ± 0.005 | 0.021 ± 0.008 | 0.025 ± 0.005 |
Spleen (mg/100 BW) | 0.266 ± 0.049 | 0.270 ± 0.105 | 0.262 ± 0.030 | 0.257 ± 0.035 | 0.357 ± 0.096 | 0.383 ± 0.079 | 0.428 ± 0.177 | 0.357 ± 0.059 |
Values represent group averages (±SEM). #Significant main effect of early life stress (ELS) (t-test using Holm’s correction).