Table 2.
Analysis of Western blot experiments of mineralocorticoid receptor (MR) and glucocorticoid receptor (GR) protein levels in dorsal hippocampus and medial prefrontal cortex (mPFC).
| MALES | FEMALES | |||||||
|---|---|---|---|---|---|---|---|---|
| MRflox/wt | MRCamKCre/wt | MRflox/wt | MRCamKCre/wt | |||||
| HC | Control | ELS | Control | ELS | Control | ELS | Control | ELS |
| MR | 1.00 ± 0.03 (9) | 1.79 ± 0.15 (8)# | 0.50 ± 0.09 (9) | 0.97 ± 0.08 (8)#@ | 1.00 ± 0.09 (6) | 1.06 ± 0.14 (5) | 0.64 ± 0.07 (6) | 0.68 ± 0.08 (6) |
| GR | 1.00 ± 0.02 (8) | 1.35 ± 0.08 (8) | 1.27 ± 0.09 (9) | 1.37 ± 0.11 (8) | 1.00 ± 0.04 (6) | 1.10 ± 0.06 (6) | 1.38 ± 0.12 (6) | 1.08 ± 0.05 (6) |
| mPFC | Control | ELS | Control | ELS | Control | ELS | Control | ELS |
| MR | 1.00 ± 0.07 (9) | 1.59 ± 0.20 (8) | 0.53 ± 0.08 (9) | 0.85 ± 0.14 (8) | 1.00 ± 0.16 (6) | 0.95 ± 0.19 (6) | 0.46 ± 0.03 (6) | 0.37 ± 0.07 (6) |
| GR | 1.00 ± 0.09 (9) | 1.09 ± 0.11 (8) | 0.89 ± 0.07 (9) | 0.88 ± 0.06 (8) | 1.00 ± 0.07 (6) | 1.06 ± 0.05 (6) | 1.10 ± 0.10 (6) | 0.94 ± 0.03 (6) |
Values indicate normalized group averages (±SEM). #Significant main effect of ELS (t-test using Holm’s correction). @Significant effect of MR genotype in ELS groups: MRflox/wt vs. MRCamKCre/wt (t-test using Holm’s correction).