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. Author manuscript; available in PMC: 2019 Aug 14.
Published in final edited form as: Science. 2019 Jun 14;364(6445):1082–1086. doi: 10.1126/science.aax0758

Fig. 3. Ripple prolongation improves memory.

Fig. 3.

(A) Schematic of the M-maze task. Red dot, reward area; blue square, start area (20-s delay).(B) Distribution of SPW-R occurrence in the M-maze (n = 33,179 SPW-Rs from 10 rats). (C and D) Fraction of correct trials (mean ± SEM) in the M-maze task during outbound (C) and inbound (D) runs in no-stimulation, ripple-prolongation, and random-stimulation sessions (total of 20 rats). ***P < 0.001; Tukey’s post-hoc test. n.s., not significant. (E) Performance ratios for the same day and animal for ripple-prolongation versus no-stimulation sessions, rippleprolongation versus random-stimulation sessions, or random-stimulation versus no-stimulation sessions in all animals (n = 20). ***P < 0.001; two-sided Wilcoxon signed-rank test. (F) Session number in which animals reached performance criterion of 80% correct trials. *P < 0.05; rank-sum test.