Table 2:
MIC (μg/ml)/ ZD (mm) values |
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | N (%) Resistant/ reduced susceptibility |
P-value | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Penicillin | MIC | 4 | 1 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 1 | 4 | 1 | 4 | 4 | 4 | 13 (81) | 0.2 |
ZD | 6 | 18 | 6 | 6 | 6 | 6 | 6 | 6 | 6 | 6 | 17 | 6 | 18 | 6 | 6 | 6 | 16 (100) | ||
Tetracycline | MIC | 16 | 16 | 16 | 16 | 16 | 16 | 16 | 16 | 16 | 16 | 16 | 16 | 16 | 16 | 16 | 16 | 16 (100) | 1.0 |
ZD | 8 | 13 | 16 | 10 | 12 | 10 | 12 | 12 | 12 | 12 | 9 | 11 | 12 | 13 | 11 | 12 | 16 (100) | ||
Gentamicin | MIC | 4 | 8 | 8 | 4 | 8 | 4 | 8 | 4 | 8 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 0 (0) | n/a |
ZD | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||
Cefixime | MIC | 0.015 | 0.015 | 0.015 | 0.015 | 0.015 | 0.015 | 0.015 | 0.015 | 0.015 | 0.015 | 0.015 | 0.015 | 0.015 | 0.015 | 0.015 | 0.015 | 0 (0) | 0.017 |
ZD | 15 | 31 | 31 | 31 | 35 | 31 | 21 | 31 | 32 | 32 | 15 | 26 | 31 | 25 | 26 | 35 | 5 (31) | ||
Ceftriaxone | MIC | 0.008 | 0.008 | 0.008 | 0.008 | 0.008 | 0.008 | 0.008 | 0.008 | 0.008 | 0.008 | 0.008 | 0.008 | 0.008 | 0.008 | 0.008 | 0.008 | 0 (0) | 0.017 |
ZD | 35 | 35 | 30 | 32 | 40 | 36 | 40 | 35 | 31 | 40 | 28 | 35 | 35 | 15 | 35 | 35 | 5 (31) | ||
Ciprofloxacin | MIC | 4 | 2 | 2 | 4 | 2 | 2 | 4 | 2 | 2 | 2 | 4 | 2 | 2 | 1 | 2 | 4 | 16 (100) | 1.0 |
ZD | 8 | 15 | 12 | 12 | 8 | 13 | 16 | 10 | 14 | 13 | 9 | 13 | 15 | 14 | 9 | 9 | 16 (100) | ||
Azithromycin | MIC | 0.06 | 0.06 | 0.25 | 0.125 | 0.125 | 0.03 | 0.06 | 0.125 | 0.06 | 0.125 | 0.125 | 0.03 | 0.03 | 0.03 | 0.03 | 0.06 | 0 (0) | n/a |
ZD | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
key: | ||||
---|---|---|---|---|
Antimicrobial | Interpretive criteria | |||
Zone diameter (ZD) breakpoint (mm) | MIC breakpoint (μg/ml) | |||
Susceptible | Resistant | Susceptible | Resistant | |
Penicillin | ≥47 | ≤26 | ≤0.06 | ≥2 |
Tetracycline | ≥38 | ≤30 | ≤0.25 | ≥2 |
Gentamicin* | - | - | <8 | >16 |
Cefixime | ≥31 | -- | ≤0.25 | - |
Ceftriaxone | ≥35 | - | ≤0.125 | - |
Ciprofloxacin | ≥41 | ≤27 | ≤0.06 | ≥1 |
Azithromycin* | - | ≤30 | <2 | ≥2 |
There are no CLSI breakpoints for gentamicin and azithromycin