Table 4.

Comparison of FETCH-questionnaire, VAS-A, and VAS-B scores at baseline (day 0), week-1 (day 8), and at the final evaluation (day 15) in dogs treated with sildenafil (n = 10) and tadalafil (n = 10) using a two-way repeated measures analysis of variance.

	Baseline		Week 1		Final			p-value
Variable	Sildenafil	Tadalafil	Sildenafil	Tadalafil	Sildenafil	Tadalafil	A	B	C
FETCH-questionnaire (0–85)	17.6 (13.9)	24.1 (19.7)	14.2 (13.2)	18.9 (17.8)	13.1 (13.8)	15.7 (18.9)	0.52	0.003	0.55
VAS-A (0–10mm)	3.96 (2.76)	2.32 (2.25)	3.04 (2.17)	2.40 (2.18)	2.77 (2.86)	2.04 (2.14)	0.29	0.31	0.52
VAS-B (0–10mm)	3.81 (2.82)	3.49 (2.85)	3.14 (1.88)	2.99 (2.03)	2.87 (2.62)	2.04 (1.61)	0.65	0.02	0.71

A: comparison of variable means for treatment regardless of time; B: comparison of variable means for time regardless of treatment; C: interaction between treatment and time; FETCH: functional evaluation of cardiac health; mm: millimeter; n: number; VAS-A: visual analog score 24 hours before evaluation period; VAS-B: visual analog score 7 days before evaluation period.