Skip to main content
. 2019 Aug 14;14(8):e0220910. doi: 10.1371/journal.pone.0220910

Table 1. Summary results of Bayesian random-effect and meta-regression models on birth outcomes affected by maternal influenza vaccination.

Birth outcomes Bayesian random-effect model Bayesian random-effect meta-regression model
Study Odds ratio P
(OR<1)
Odds ratio
(vaccination season)
P
(OR<1)
Odds ratio
(income level)
P
(OR<1)
Posterior median 95% CrI Posterior median 95% CrI Posterior median 95% CrI
PTB SD (τ) 0.094 0.101 0.086
Overall 0.945 0.736 1.345 0.733 0.837 0.566 1.278 0.844 1.019 0.784 1.364 0.414
RCT overall 0.954 0.787 1.224 0.707 0.847 0.606 1.201 0.848 1.003 0.816 1.260 0.484
Cohort overall 0.916 0.859 0.977 0.995 0.798 0.608 1.029 0.960 1.016 0.905 1.143 0.393
Case-control overall 0.970 0.762 1.439 0.601 0.868 0.593 1.369 0.765 1.039 0.804 1.449 0.359
LBW SD (τ) 0.107 0.119 0.120
Overall 0.928 0.432 2.112 0.766 0.508 0.045 4.655 0.714 0.952 0.405 2.335 0.642
RCT overall 0.926 0.721 1.238 0.800 0.500 0.066 3.669 0.727 0.938 0.714 1.301 0.723
Cohort overall 0.932 0.864 0.998 0.978 0.521 0.072 3.736 0.715 0.966 0.786 1.165 0.644
SGA SD (τ) 0.123 0.124 0.125
Overall 0.971 0.249 4.217 0.633 1.202 0.273 4.783 0.728 0.975 0.205 4.482 0.608
RCT overall 0.964 0.475 2.010 0.666 1.189 0.538 2.685 0.264 0.965 0.478 2.051 0.653
Cohort overall 0.976 0.947 1.004 0.955 1.211 0.798 1.892 0.851 0.981 0.927 1.039 0.768
Con-genital mal-formation SD (τ) 0.100 0.103 0.102
Overall 1.026 0.687 1.600 0.380 1.383 0.814 2.459 0.086 1.005 0.643 1.577 0.480
RCT overall 1.032 0.659 1.709 0.390 1.393 0.795 2.576 0.095 1.002 0.610 1.621 0.494
Cohort overall 1.026 0.955 1.108 0.220 1.384 0.961 2.058 0.040 1.007 0.891 1.173 0.451
Case-control overall 1.022 0.706 1.499 0.410 1.374 0.827 2.347 0.087 1.004 0.677 1.504 0.487
Fetal death SD (τ) 0.222 0.191 0.203
Overall 0.942 0.560 1.954 0.616 0.732 0.372 1.681 0.821 0.977 0.578 1.885 0.550
RCT overall 1.002 0.686 1.679 0.497 0.767 0.414 1.525 0.791 1.023 0.693 1.673 0.454
Cohort overall 0.822 0.718 0.931 0.996 0.643 0.391 1.100 0.951 0.857 0.655 1.102 0.919
Case-control overall 1.077 0.719 1.833 0.385 0.814 0.433 1.672 0.726 1.098 0.724 1.832 0.343

CrI: Credible Interval,

SD (τ): Standard deviation between studies (estimation of heterogeneity between studies)