Table 1. Preoperative characteristics of HCC patients classified according to AT VO2 change.
| Variables | Maintenance (n = 78) |
Decrease (n = 28) |
P | ||
|---|---|---|---|---|---|
| Age, yr | 70 | (63.0, 73.0) | 73 | (67.8, 75.0) | 0.023 |
| Sex | 0.604 | ||||
| Male | 61 | (78%) | 20 | (71%) | |
| Female | 17 | (22%) | 8 | (29%) | |
| ASA-PS | 0.227 | ||||
| 1 | 8 | (10%) | 0 | (0%) | |
| 2 | 65 | (83%) | 26 | (93%) | |
| 3 | 5 | (6%) | 2 | (7%) | |
| Alcohol intake | 0.112 | ||||
| None | 53 | (68%) | 14 | (50%) | |
| Positive | 25 | (32%) | 14 | (50%) | |
| Exercise | 0.004 | ||||
| Implemented | 50 | (64%) | 9 | (32%) | |
| Not-implemented | 28 | (36%) | 19 | (68%) | |
| Diabetes | 0.805 | ||||
| Absent | 58 | (74%) | 20 | (71%) | |
| Present | 20 | (26%) | 8 | (29%) | |
| Hypertension | 0.260 | ||||
| Absent | 50 | (64%) | 14 | (50%) | |
| Present | 28 | (36%) | 14 | (50%) | |
| Esophageal and/or gastric varices | 1.000 | ||||
| Absent | 74 | (95%) | 27 | (96%) | |
| Present | 4 | (5%) | 1 | (4%) | |
| HBsAg | 0.389 | ||||
| Negative | 63 | (81%) | 25 | (89%) | |
| Positive | 15 | (19%) | 3 | (11%) | |
| HCVAb | 0.825 | ||||
| Negative | 45 | (58%) | 15 | (54%) | |
| Positive | 33 | (42%) | 13 | (46%) | |
| Child–Pugh class | 1.000 | ||||
| A | 76 | (97%) | 27 | (96%) | |
| B | 2 | (3%) | 1 | (4%) | |
| ICGR15, % | 13.2 | (9.7, 19.0) | 12.5 | (9.7, 20.1) | 0.848 |
| WBC, 102/μL | 50.5 | (41.0, 60.0) | 50.5 | (41.0, 64.3) | 0.739 |
| Hemoglobin, g/dL | 13.1 | (12.4, 14.2) | 12.7 | (11.5, 14.0) | 0.060 |
| Hematocrit, % | 37.2 | (35.4, 39.9) | 37.2 | (34.4, 40.1) | 0.571 |
| Platelet count, ×104/mm3 | 14.6 | (11.5, 18.7) | 16.5 | (13.3, 19.4) | 0.337 |
| Albumin, g/dL | 4.1 | (3.8, 4.3) | 3.9 | (3.7, 4.3) | 0.371 |
| AST, U/L | 35.5 | (23.5, 50.8) | 38.0 | (28.5, 66.5) | 0.488 |
| ALT, U/L | 35.0 | (23.0, 53.8) | 38.0 | (20.5, 59.5) | 0.761 |
| Prothrombin activity, % | 88.6 | (81.7, 96.1) | 84.0 | (76.0, 92.7) | 0.121 |
| ALP, U/L | 248.0 | (187.8, 346.0) | 298.0 | (256.8, 347.5) | 0.050 |
| γGTP, U/L | 58.5 | (32.8, 104.3) | 48.0 | (31.0, 88.0) | 0.495 |
| Cholinesterase, U/L | 254.0 | (197.0, 275.0) | 221.0 | (175.0, 287.5) | 0.231 |
| Total bilirubin, mg/dL | 0.8 | (0.6, 0.9) | 0.6 | (0.5, 0.9) | 0.252 |
| Creatinine, mg/dL | 0.8 | (0.6, 0.9) | 0.8 | (0.7, 1.0) | 0.099 |
| CRP, mg/dL | 0.1 | (0.0, 0.2) | 0.1 | (0.0, 0.2) | 0.830 |
| Triglyceride, mg/dL | 104.0 | (75.5, 133.0) | 91.0 | (72.0, 120.0) | 0.241 |
| Total cholesterol, mg/dL | 163.5 | (141.3, 179.0) | 171.0 | (141.0, 190.0) | 0.467 |
| Glucose, mg/dL | 106.0 | (94.0, 140.3) | 102.0 | (94.0, 131.0) | 0.685 |
| Insulin, μIU/mL | 12.6 | (6.3, 19.2) | 13.0 | (8.3, 26.8) | 0.520 |
| HbA1c | 5.6 | (5.3, 6.7) | 5.5 | (5.0, 5.8) | 0.095 |
| Alpha-fetoprotein, ng/mL | 7.2 | (3.7, 15.6) | 11.0 | (4.7, 64.4) | 0.313 |
| PIVKA-II | 39.5 | (18.0, 151.0) | 109.5 | (22.5, 1246.3) | 0.126 |
Data are shown as median (5th percentile, 95th percentile) or n (%).
AT, anaerobic threshold; VO2, oxygen consumption; ASA-PS, The American Society of Anesthesiologists physical status; HBsAg, hepatitis B surface antigen; HCVAb, hepatitis C virus antibody; ICGR15, indocyanine green retention rate at 15 min; WBC, white blood cell count; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; γGTP, γ-glutamyltranspeptidase; CRP, C-reactive protein; HbA1c, glycated hemoglobin; PIVKA-II, protein induced by vitamin K absence-II.