Table 1.
Characteristics of Subjects with Stroke
| Demographics/medical history | ||
| Age, mean yr±SD | 58±14 | |
| Gender, M/F | 19/8 | |
| Hand dominance, R/L/A | 24/3/0 | |
| Diabetes mellitus, yes/no | 6/21 | |
| Hypertension, yes/no | 15/12 | |
| Hypercholesterolemia, yes/no | 15/12 | |
| Geriatric Depression Scale, mean±SD | 4.07±3.73 | |
| Time post-stroke, median mo [IQR] | 30 [9-44] | |
| Stroke type, ischemic/hemorrhagic | 18/9 | |
| Stroke hemisphere, L/R | 13/14 | |
| Stroke in dominant hemisphere, yes/no | 13/14 | |
| NIHSS, normal = 0 | 2.41±2.25 | |
| Sensorimotor Behavior, mean±SD | Contralesional | Ipsilesional |
| ARAT, normal = 57 | 32.74±22.41 | |
| FM Arm Motor, normal = 66 | 45.9±11.7 | |
| FM Arm Sensory, normal = 12 | 10.89±2.42 | 12.00±0.00 |
| B&B score | 22.2±18.0 | 55.9±8.2 |
| NHPT score | 54.6±10.7 | 25.1±7.9 |
| FT score | 14.4±12.3 | 47.2±10.2 |
| Brain injury | ||
| Infarct volume, cm3, mean±SD | 20.6±23.4 | |
| M1 injury, yes/no | 5/20 | |
| M1 % injury, mean±SD | 10.1±21.1 | |
| S1 injury, yes/no | 7/18 | |
| S1 % injury, mean±SD | 17.0±30.8 | |
| S2 injury, yes/no | 9/16 | |
| S2 % injury, mean±SD | 11.6±24.7 | |
| CST injury, yes/no | 18/2 | |
| CST % injury, mean±SD | 34.3±28.7 | |
| TST injury, yes/no | 17/3 | |
| TST % injury, mean±SD | 7.5±6.7 | |
| Total motor system injury | 0.9±0.8 | |
| Total sensory system injury | 0.05±0.7 | |
| Cortical function, mean (SD) | Contralesional | Ipsilesional |
| M1 activation volume, voxels | 24.9±34.1 | 51.4±39.2 |
| S1 activation volume, voxels | 36.0±33.5 | 53.3±39.9 |
| S2 activation volume, voxels | 107.8±89.5 | 132.8±108.5 |
| M1 activation, contrast estimate | 2.0±1.9 | 3.7±2.0 |
| S1 activation, contrast estimate | 2.1±1.1 | 2.8±1.5 |
| S2 activation, contrast estimate | 2.4±1.5 | 2.3±1.7 |
| Cortical connectivity, mean (SD) | ||
| iM1-cM1 correlation coefficient | 0.18±0.21 | |
| iM1-iS1 correlation coefficient | 0.45±0.19 | |
| iM1-iS2 correlation coefficient | 0.09±0.19 | |
| iS1-cS1 correlation coefficient | 0.14±0.20 | |
| iS1-iS2 correlation coefficient | 0.08±0.21 | |
| iS2-cS2 correlation coefficient | 0.27±0.21 | |
A = ambidextrous; ARAT = Action Arm Research Test; B&B = Box & Blocks; c = contralesional; CST = corticospinal tract; F = female; FM = Fugl-Meyer; FT = Finger Tapping; i = ipsilesional; IQR = interquartile range; L = left; M = male; M1 = primary motor cortex; NHPT = Nine Hole Peg Test; NIHSS = NIH stroke scale; R = right; S1 = primary somatosensory cortex; S2 = secondary somatosensory cortex; SD = standard deviation; TST = thalamocortical sensory tract.