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. Author manuscript; available in PMC: 2020 Aug 14.
Published in final edited form as: J Cell Physiol. 2019 Feb 14;234(9):16376–16388. doi: 10.1002/jcp.28306

Figure 3.

Figure 3

Flow rate and amount of saliva in response to β-adrenergic vs. cholinergic stimulation of the ex vivo SMG. The mouse ex vivo SMG was stimulated for 20 min with 1.0 μM IPR, followed by 15 min washout, and finally 10 min perfusion with 0.3 μM CCh in physiological Solution A (Table 2). (a) No differences in the kinetics and rates of salivation (μl/min) were observed in response to 1.0 μM IPR or 0.3 μM CCh, respectively, in the SMG of Slc4a7+/+ (white circles, n = 11) and Slc4a7−/− (black circles, n = 15) mice. (b) The saliva amount (μl) of the ex vivo stimulated SMG in response to 1.0 μM IPR, and (c) in response to 0.3μM CCh were comparable in Slc4a7+/+ (white bars) and Slc4a7−/− mice (grey bars). Values are shown for individual glands (circles) along with the mean ± SEM.