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. Author manuscript; available in PMC: 2020 Aug 14.
Published in final edited form as: J Cell Physiol. 2019 Feb 14;234(9):16376–16388. doi: 10.1002/jcp.28306

Figure 4.

Figure 4

Flow rate and amount of saliva in response to physiological-like β-adrenergic and cholinergic stimulation of the ex vivo SMG. The mouse ex vivo SMG was stimulated for 10 min with the β-adrenergic receptor agonist IPR (1.0 μM) plus the cholinergic receptor agonist CCh (0.3 μM) in physiological Solution A (Table 2). (a) No differences in the kinetics and rates of salivation (μl/min) were observed between Slc4a7+/+ (white circle, n=14) and Slc4a7−/− mice (black circle, n=15). (b) The saliva amount (μl) of the ex vivo stimulated SMG was comparable in Slc4a7+/+ (white bars) and Slc4a7−/− mice (grey bars). Values are shown for individual glands (circles) along with the mean ± SEM.