Table 3.
Receiver operating characteristic analysis of models predicting previous fracture based on combinations of BMD, bone microarchitectural and FEA parameters
Model | Predictors | AUC (95% CI) |
---|---|---|
Men | ||
1 | Femoral neck aBMD | 0.61 (0.52, 0.68) |
2 | Femoral neck aBMD | 0.67 (0.60, 0.75) |
Total area | ||
Cortical thickness | ||
Trabecular separation | ||
Women | ||
1 | Femoral neck aBMD | 0.70 (0.63, 0.78) |
2 | Femoral neck aBMD | 0.76 (0.69, 0.83) |
Cortical area | ||
Cortical porosity | ||
Trabecular density | ||
Trabecular thickness | ||
3 | Femoral neck aBMD | 0.78 (0.70, 0.84) |
Cortical area | ||
Cortical porosity | ||
Trabecular density | ||
Trabecular thickness | ||
Bone failure load | ||
Young modulus | ||
Von Mises stresses (trabecular) |
aBMD areal bone mineral density; FEA finite element analysis; AUC area under receiver operator characteristic curve