Table 2. Allele frequencies and the association between SNPs and PACG under the allelic model.

Gene	SNP	CHR	BP	Minor allele	Genotype (AA/Aa/aa)a		MAF		HWE-P		OR (95%CI)	P
					Case	Control	Case	Control	Case	Control
MYOC	rs12076134	1	171606054	G	331/150/19	468/218/33	0.188	0.198	0.662	0.2401	0.954 (0.759-1.198)	0.6828
MYOC	rs183532	1	171609481	T	295/181/24	402/271/47	0.229	0.254	0.7037	0.9215	0.781 (0.629-0.969)	0.025
MYOC	rs235875	1	171613756	T	239/204/57	363/300/57	0.318	0.287	0.1813	0.716	1.171 (0.964-1.423)	0.1124
MYOC	rs235913	1	171618656	T	193/225/82	237/363/120	0.389	0.419	0.2586	0.3589	0.883 (0.733-1.063)	0.1895
ABCA1	rs2422493	9	107690995	A	175/242/83	232/374/114	0.408	0.418	1	0.0782	0.968 (0.801-1.171)	0.7397
ABCA1	rs2487042	9	107694522	T	262/192/46	366/296/58	0.284	0.286	0.2262	0.9274	0.959 (0.783-1.173)	0.6817
ABCA1	rs2472496	9	107695353	A	169/237/94	223/372/125	0.425	0.433	0.5219	0.1718	0.979 (0.812-1.181)	0.8267
ABCA1	rs2472493	9	107695848	A	149/245/106	195/382/142	0.457	0.464	0.7871	0.0722	0.992 (0.822-1.197)	0.9303
ABCA1	rs2487032	9	107703934	A	156/239/105	202/374/143	0.449	0.459	0.4697	0.2295	0.942 (0.782-1.135)	0.5304
ABCA1	rs2472459	9	107710562	T	250/196/54	350/306/64	0.304	0.302	0.1124	0.8596	0.981 (0.804-1.196)	0.8476
ABCA1	rs2472519	9	107715878	G	236/202/62	333/314/71	0.326	0.318	0.0832	0.8634	0.984 (0.809-1.196)	0.8691

SNP: Single nucleotide polymorphisms; PACG: Primary angle-closure glaucoma; CHR: Chromosome; BP: Base pair position; MAF: Minor allele frequency; HWE-P: The P-value of Hardy-Weinburg equilibrium; OR: Odds ratio; CI: Confidence intervals. P, OR, and CI were calculated with logistic regression model by adjusting for age and gender under the allelic model with the major allele as reference. ^aA represents the wild allele and a represents the minor allele.