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. 2019 Aug 18;12(8):1317–1322. doi: 10.18240/ijo.2019.08.13

Table 3. Genotype distribution of target SNPs in cases and controls.

Gene SNP Dominant model
Recessive model
Aa+aaa AAa Aa+aab AAb OR (95%CI) P aaa AA+Aaa aab AA+Aab OR (95%CI) P
MYOC rs12076134 169 331 251 468 0.960 (0.732-1.26) 0.769 19 481 33 686 0.858 (0.447-1.649) 0.647
MYOC rs183532 205 295 318 402 0.748 (0.575-0.972) 0.029 24 476 47 673 0.707 (0.403-1.242) 0.228
MYOC rs235875 261 239 357 363 1.114 (0.861-1.441) 0.412 57 443 57 663 1.595 (1.04-2.446) 0.032
MYOC rs235913 307 193 483 237 0.776 (0.593-1.015) 0.064 82 418 120 600 0.987 (0.698-1.397) 0.942
ABCA1 rs2422493 325 175 488 232 0.852 (0.649-1.12) 0.251 83 417 114 606 1.168 (0.822-1.661) 0.386
ABCA1 rs2487042 238 262 354 366 0.858 (0.663-1.11) 0.243 46 454 58 662 1.324 (0.831-2.112) 0.238
ABCA1 rs2472496 331 169 497 223 0.836 (0.635-1.101) 0.203 94 406 125 595 1.221 (0.873-1.71) 0.244
ABCA1 rs2472493 351 149 524 195 0.861 (0.647-1.146) 0.305 106 394 142 577 1.18 (0.855-1.628) 0.314
ABCA1 rs2487032 344 156 517 202 0.795 (0.599-1.055) 0.112 105 395 143 576 1.126 (0.816-1.554) 0.471
ABCA1 rs2472459 250 250 370 350 0.865 (0.668-1.119) 0.270 54 446 64 656 1.401 (0.899-2.183) 0.137
ABCA1 rs2472519 264 236 385 333 0.846 (0.653-1.095) 0.204 62 438 71 647 1.443 (0.95-2.192) 0.086

SNP: Single nucleotide polymorphisms; OR: Odds ratio; CI: Confidence intervals. aThe genotype counts in cases; bThe genotype counts in controls; a represents the minor allele, A represents the wild allele; Dominant model: Aa+aa compared with AA; Recessive model: aa compared with AA+Aa. P, OR, and CI were calculated with logistic regression model by adjusting for age and gender.