. 2019 Aug 18;12(8):1317–1322. doi: 10.18240/ijo.2019.08.13

Table 4. Haplotype frequencies in PACG and control cohorts.

Block	SNPs	Haplotype	f¹ (%)	f² (%)	OR^a	P^a	P-permutation^b
Block 1	rs2487042, rs2472496, rs2472493	TAA	0.283	0.286	0.958	0.679	0.9998
		CAA	0.14	0.146	1.01	0.913	1
		CGA	0.034	0.031	1.2	0.493	0.9967
		CGG	0.541	0.537	0.998	0.98	1
Block 2	rs2487032, rs2472459, rs2472519	ATG	0.303	0.293	1.01	0.905	1
		ACG	0.018	0.019	0.72	0.334	0.9671
		ACA	0.127	0.141	0.948	0.691	1
		GCA	0.546	0.534	1.06	0.536	0.9981
Block 3	rs12076134, rs183532, rs235875	TCT	0.315	0.284	1.18	0.104	0.6279
		TTC	0.223	0.253	0.77	0.018	0.1576
		GCC	0.179	0.196	0.94	0.598	0.999
		TCC	0.274	0.264	1.1	0.34	0.9693

OR: Odds ratio; f¹: Haplotype frequencies in cases; f²: Haplotype frequencies in controls. ^aOR and P value were calculated with logistic regression model by adjusting for age and gender. ^bA total of 10 000 permutations were performed.