Table 5. Association between SNPs and AL and ACD.
Gene | SNP | Minor allele | ACD (2.74±0.474; 0.67-3.51)a |
AL (22.92±0.891; 20.01-25.51)a |
||||
β | SE | P | β | SE | P | |||
MYOC | rs12076134 | G | 0.008 | 0.0194 | 0.674 | -0.009 | 0.037 | 0.817 |
MYOC | rs183532 | T | 0.027 | 0.0178 | 0.132 | -0.015 | 0.0345 | 0.667 |
MYOC | rs235875 | T | -0.017 | 0.0175 | 0.330 | -0.010 | 0.0328 | 0.757 |
MYOC | rs235913 | T | 0.008 | 0.0158 | 0.617 | 0.014 | 0.0290 | 0.635 |
ABCA1 | rs2422493 | A | 0.009 | 0.0162 | 0.598 | 0.017 | 0.0319 | 0.592 |
ABCA1 | rs2487042 | T | 0.009 | 0.0174 | 0.594 | -0.014 | 0.0338 | 0.688 |
ABCA1 | rs2472496 | A | 0.014 | 0.0161 | 0.395 | 0.006 | 0.0314 | 0.85 |
ABCA1 | rs2472493 | A | 0.013 | 0.0160 | 0.405 | -0.011 | 0.0313 | 0.725 |
ABCA1 | rs2487032 | A | -0.005 | 0.0161 | 0.758 | 0.025 | 0.0301 | 0.407 |
ABCA1 | rs2472459 | T | -0.0001 | 0.0178 | 0.996 | -0.013 | 0.0342 | 0.714 |
ABCA1 | rs2472519 | G | -0.003 | 0.0173 | 0.844 | 0.010 | 0.0337 | 0.770 |
SNP: Single nucleotide polymorphisms; AL: Axial length; ACD: Anterior chamber depth; β: Per-allele effect of the minor allele; SE: Standard error; P: P-value for association adjusting for age and gender. aThe mean±SD and the range of measured values for AL or ACD.