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. 2019 Aug 8;10:701. doi: 10.3389/fgene.2019.00701

Table 3.

Summary of microbial genes identified for the prediction of ADG.

KEGG id Description Gene name abbreviation Pathways Mean abundance PLS estimate VIP Cluster
K01448 N-acetylmuramoyl-L-alanine amidase amiABC 2Cationic antimicrobial peptide (CAMP) resistance 0.0236 −0.1937 1.22 06
K00133 Aspartate-semialdehyde dehydrogenase asd 2Metabolic pathways; microbial metabolism in diverse environments; biosynthesis of secondary metabolites; biosynthesis of antibiotics; glycine, serine and threonine metabolism; monobactam biosynthesis; cysteine and methionine metabolism; lysine biosynthesis; 2-oxocarboxylic acid metabolism; biosynthesis of amino acids 0.1197 −0.0684 1.20 NC
K01912 Phenylacetate-CoA ligase paaK 2Microbial metabolism in diverse environments; phenylalanine metabolism; biofilm formation—Vibrio cholerae 0.1543 −0.0980 1.16 16
K02919 Large subunit ribosomal protein L36 rpmJ 2Ribosome 0.0261 −0.1884 1.04 NC
K02879 Large subunit ribosomal protein L17 rplQ 2Ribosome 0.0773 0.0746 1.00 21
K02113 F-type H+-transporting ATPase subunit delta atpH 2Metabolic pathways; oxidative phosphorylation; photosynthesis 0.0292 −0.0486 1.00 21
K00283 Glycine dehydrogenase subunit 2 gcvPB 2Metabolic pathways; biosynthesis of secondary metabolites; biosynthesis of antibiotics; glycine, serine and threonine metabolism; glyoxylate and dicarboxylate metabolism; carbon metabolism 0.0284 0.0502 0.99 25
K03775 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD slyD 5Posttranslational modification, protein turnover, chaperones 0.0139 0.0672 0.93 22
K07561 Diphthamide synthase subunit DPH2 dph2 5Translation, ribosomal structure, and biogenesis 0.0030 0.2310 1.20 01
K01925 UDP-N-acetylmuramoylalanine–D-glutamate ligase murD 2Metabolic pathways; D-glutamine and D-glutamate metabolism; peptidoglycan biosynthesis 0.0620 0.1155 1.15 1
K02437 Glycine cleavage system H protein gcvH 2Metabolic pathways; biosynthesis of secondary metabolites; biosynthesis of antibiotics; glycine, serine and threonine metabolism; glyoxylate and dicarboxylate metabolism; carbon metabolism 0.0069 0.1209 1.08 1
K03530 DNA-binding protein HU-beta hupB 5DNA binding protein: replication, recombination, and repair 0.0331 0.1062 1.07 19
K02600 N utilization substance protein A nusA 5Transcription 0.1126 0.0726 1.02 1
K02518 Translation initiation factor IF-1 infA 5Translation, ribosomal structure, and biogenesis 0.0346 0.0646 0.98 21

Each column respectively presents information about: 1) KEGG identifier, 2) description of the gene (from KEGG), 3) gene name abbreviation, 4) metabolic pathways in which this gene participates, 5) mean relative abundance of the microbial gene in 42 animals, 6) the partial least squares (PLS) estimate of the regression coefficient using three latent variables, 7) the variable importance in projection (VIP) calculated during the PLS analysis using three latent variables, and 8) the cluster in which the microbial gene was allocated in the final network. 1Microbial genes excluded from the final network due to the 0.80 minimum correlation threshold. NC, Microbial genes not clustered in the final network. Information retrieved from: 2KEGG database, 3NCBI database, 4BioCyc database, and 5UniProt database. The genes in this table explained 65.4% of the variation in ADG (average daily gain). Rows colored in gray correspond to genes simultaneously identified for both FCR (feed conversion ratio) and ADG prediction.