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. 2019 Aug 8;10:701. doi: 10.3389/fgene.2019.00701

Table 4.

Summary of microbial genes identified for the prediction of RFI.

KEGG id Description Gene name abbreviation Pathways Mean abundance PLS estimate VIP Cluster
K03406 Methyl-accepting chemotaxis protein mcp 2Two-component system; bacterial chemotaxis 0.0225 −0.0510 1.26 1
K03413 Two-component system, chemotaxis family, response regulator CheY cheY 2Two-component system; bacterial chemotaxis 0.0018 0.0478 1.16 1
K01534 Cd2+/Zn2+-exporting ATPase zntA 5Cation-transporting ATPase activity; metal ion binding; nucleotide binding 0.0211 −0.0653 1.16 04
K07258 serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) dacC 2Metabolic pathways; Peptidoglycan biosynthesis 0.0049 −0.0375 1.14 1
K07301 Cation:H+ antiporter yrbG 3Inorganic ion transport and metabolism 0.0096 −0.0145 1.09 04
K04720 Threonine-phosphate decarboxylase cobD 2Porphyrin and chlorophyll metabolism 0.0034 −0.0501 1.06 04
K03407 Two-component system, chemotaxis family, sensor kinase CheA cheA 2Two-component system; bacterial chemotaxis 0.0048 −0.0236 1.04 1
K00595 Precorrin-6Y C5,15-methyltransferase (decarboxylating) cobL 2Metabolic pathways; porphyrin and chlorophyll metabolism 0.0078 0.0223 1.02 04
K01571 Oxaloacetate decarboxylase, alpha subunit oadA 2Metabolic pathways; pyruvate metabolism 0.0165 −0.0501 0.96 04
K02057 Simple sugar transport system permease protein ABC.SS.P 3Carbohydrate transport and metabolism 0.0023 −0.1375 0.96 20
K02390 Flagellar hook protein FlgE flgE 2Flagellar assembly 0.0015 −0.0376 0.87 1
K02417 Flagellar motor switch protein FliN/FliY fliN 2Bacterial chemotaxis; flagellar assembly 0.0018 −0.1120 0.77 1
K03738 Aldehyde:ferredoxin oxidoreductase aor 2Metabolic pathways; Microbial metabolism in diverse environments; Pentose phosphate pathway; Carbon metabolism 0.0144 −0.0657 0.68 NC
K02009 Cobalt transport protein cbiN 2ABC transporters 0.0074 −0.1126 0.67 01
K01709 CDP-glucose 4,6-dehydratase rfbG 2Metabolic pathways; amino sugar and nucleotide sugar metabolism 0.0041 0.2549 1.46 1
K00978 Glucose-1-phosphate cytidylyltransferase rfbF 2Metabolic pathways; amino sugar and nucleotide sugar metabolism; starch and sucrose metabolism 0.0042 0.2056 1.23 1
K14113 Energy-converting hydrogenase B subunit D ehbD 0.0010 0.1703 1.00 NC

Each column respectively presents information about: 1) KEGG identifier, 2) description of the gene (from KEGG), 3) gene name abbreviation, 4) metabolic pathways in which this gene participates, 5) mean relative abundance of the microbial gene in 42 animals, 6) the partial least squares (PLS) estimate of the regression coefficient using three latent variables, 7) the variable importance in projection (VIP) calculated during the PLS analysis using three latent variables, and 8) the cluster in which the microbial gene was allocated in the final network. 1Microbial genes excluded from the final network due to the 0.80 minimum correlation threshold. NC, Microbial genes not clustered in the final network. Information retrieved from: 2KEGG database, 3NCBI database, 4BioCyc database, and 5UniProt database. The genes in this table explained 65.6% of the variation in RFI (residual feed intake). Rows colored in grey correspond to genes simultaneously identified for both RFI and DFI (daily feed intake) prediction.