Table 2.
Cluster defining gene lists from day 14 sorted CD38+HLA-DR+ CD8+ T cell scRNAseq analysis
| Cluster 1 | Cluster 2 | Cluster 3 | Cluster 4 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ensembl ID | Gene Name | P-Value | Log2 FC | Ensembl ID | Gene Name | p-Value | Log2 FC | Ensembl ID | Gene Name | P-Value | Log2 FC | Ensembl ID | Gene Name | P-Value | Log2 FC |
| ENSG00000176890 | TYMS | 4.53E-33 | 8.03 | ENSG00000265972 | TXNIP | 4.93E-13 | 2.21 | ENSG00000126353 | CCR7 | 5.01E-08 | 1.94 | ENSG00000111796 | KLRB1 | 1.51E-22 | 3.77 |
| ENSG00000100450 | GZMH | 8.67E-29 | 3.54 | ENSG00000172005 | MAL | 1.05E-10 | 2.25 | ENSG00000109321 | AREG | 2.19E-05 | 1.83 | ENSG00000160789 | LMNA | 1.16E-11 | 2.77 |
| ENSG00000182054 | IDH2 | 1.58E-25 | 3.15 | ENSG00000100100 | PIK3IP1 | 6.62E-08 | 1.79 | ENSG00000172005 | MAL | 2.26E-05 | 1.68 | ENSG00000124762 | CDKN1A | 1.29E-09 | 2.72 |
| ENSG00000145649 | GZMA | 5.86E-25 | 3.10 | ENSG00000138795 | LEF1 | 1.46E-07 | 1.83 | ENSG00000171223 | JUNB | 9.93E-03 | 1.07 | ENSG00000107742 | SPOCK2 | 6.97E-04 | 1.39 |
| ENSG00000117632 | STMN1 | 5.84E-24 | 3.80 | ENSG00000081059 | TCF7 | 2.25E-07 | 1.73 | ENSG00000227507 | LTB | 2.98E-02 | 0.98 | ENSG00000120129 | DUSP1 | 2.11E-03 | 1.30 |
| ENSG00000196126 | HLA-DRB1 | 7.29E-21 | 3.18 | ENSG00000179144 | GIMAP7 | 6.65E-07 | 1.69 | ENSG00000130844 | ZNF331 | 3.44E-02 | 0.98 | ENSG00000177606 | JUN | 3.66E-03 | 1.30 |
| ENSG00000137441 | FGFBP2 | 1.83E-20 | 3.19 | ENSG00000131507 | NDFIP1 | 1.02E-04 | 1.36 | ENSG00000131507 | NDFIP1 | 3.85E-02 | 0.94 | ENSG00000198355 | PIM3 | 4.45E-03 | 1.32 |
| ENSG00000222041 | LINC00152 | 2.24E-19 | 2.78 | ENSG00000114861 | FOXP1 | 2.21E-04 | 1.34 | ENSG00000100100 | PIK3IP1 | 3.90E-02 | 0.96 | ENSG00000100906 | NFKBIA | 1.23E-02 | 1.13 |
| ENSG00000235162 | C12orf75 | 4.16E-19 | 2.64 | ENSG00000169508 | GPR183 | 2.81E-04 | 1.39 | ENSG00000112245 | PTP4A1 | 4.44E-02 | 0.96 | ENSG00000160888 | IER2 | 1.31E-02 | 1.12 |
| ENSG00000213719 | CLIC1 | 8.58E-18 | 2.39 | ENSG00000132424 | PNISR | 1.18E-03 | 1.19 | ENSG00000196352 | CD55 | 7.50E-02* | 0.88 | ENSG00000128016 | ZFP36 | 1.31E-02 | 1.15 |
| ENSG00000100453 | GZMB | 9.00E-18 | 3.16 | ENSG00000108848 | LUC7L3 | 1.74E-03 | 1.21 | ENSG00000171522 | PTGER4 | 7.68E-02* | 0.87 | ENSG00000168685 | IL7R | 1.40E-02 | 1.12 |
| ENSG00000103187 | COTL1 | 1.10E-16 | 2.27 | ENSG00000152558 | TMEM123 | 4.46E-03 | 1.09 | ENSG00000081059 | TCF7 | 7.89E-02* | 0.88 | ENSG00000144655 | CSRNP1 | 1.45E-02 | 1.17 |
| ENSG00000153563 | CD8A | 1.35E-16 | 2.34 | ENSG00000245164 | LINC00861 | 5.02E-03 | 1.15 | ENSG00000119801 | YPEL5 | 9.27E-02* | 0.81 | ENSG00000092820 | EZR | 2.44E-02 | 1.08 |
| ENSG00000204287 | HLA-DRA | 3.11E-14 | 2.75 | ENSG00000227507 | LTB | 8.35E-03 | 1.04 | ENSG00000163682 | RPL9 | 9.60E-02* | 0.80 | ENSG00000170345 | FOS | 3.53E-02 | 1.06 |
| ENSG00000019582 | CD74 | 4.11E-14 | 2.13 | ENSG00000251562 | MALAT1 | 8.82E-03 | 0.99 | ENSG00000138795 | LEF1 | 1.13E-01* | 0.86 | ENSG00000152518 | ZFP36L2 | 6.28E-02* | 0.96 |
| ENSG00000111640 | GAPDH | 4.11E-14 | 2.61 | ENSG00000099204 | ABLIM1 | 9.11E-03 | 1.05 | ENSG00000167552 | TUBA1A | 1.15E-01* | 0.80 | ENSG00000188229 | TUBB4B | 7.09E-02* | 1.02 |
| ENSG00000271503 | CCL5 | 4.11E-14 | 2.73 | ENSG00000126353 | CCR7 | 1.27E-02 | 1.06 | ENSG00000168421 | RHOH | 1.29E-01* | 0.79 | ENSG00000102760 | RGCC | 7.12E-02* | 0.99 |
| ENSG00000184009 | ACTG1 | 4.11E-14 | 2.28 | ENSG00000188404 | SELL | 1.42E-02 | 0.98 | ENSG00000111678 | C12orf57 | 1.42E-01* | 0.75 | ENSG00000143384 | MCL1 | 7.30E-02* | 0.98 |
| ENSG00000105374 | NKG7 | 4.11E-14 | 2.71 | ENSG00000127528 | KLF2 | 1.88E-02 | 0.94 | ENSG00000059804 | SLC2A3 | 1.48E-01* | 0.75 | ENSG00000168209 | DDIT4 | 7.39E-02* | 0.99 |
| ENSG00000172531 | PPP1CA | 4.96E-14 | 2.05 | ENSG00000108654 | DDX5 | 3.22E-02 | 0.88 | ENSG00000144713 | RPL32 | 1.57E-01* | 0.72 | ENSG00000095794 | CREM | 8.85E-02* | 0.95 |
*not significant