TABLE 1.
Empty | |||||
Stage |
Cdk13+/+ |
Cdk13tm1a/+ |
Cdk13tm1a/tm1a |
Litters | decidua |
(25%) | (50%) | (25%) | |||
E9.5 | 4 (21.1%) | 12 (63.2%) | 3 (15.8%)* | 3 | 2 |
E10.5 | 4 (20%) | 10 (50%) | 6 (30%)* | 2 | 0 |
E11.5 | 14 (31.8%) | 23 (52.3%) | 7 (15.9%)* | 6 | 4 |
E12.5 | 31 (30.7%) | 52 (51.5%) | 18 (17.8%)*,# | 15 | 13 |
E13.5 | 6 (16.2%) | 18 (48.6%) | 13 (35.1%)* | 5 | 5 |
E14.5 | 48 (27.6%) | 95 (54.6%) | 31 (17.8%)*,# | 26 | 9 |
E15.5 | 21 (27.5%) | 34 (58%) | 10 (14.5%)* | 11 | 5 |
E16.5 | 8 (25%) | 18 (56.3%) | 6 (18.7%)*,# | 4 | 0 |
P0 | 39 (33.1%) | 79 (66.9%) | 0 | 28 |
*Growth retardation, #dead embryo.